Varenicline

Varenicline, previously known as Champix, works by reducing symptoms of withdrawal and blocking some of the ‘rewarding’ effects of smoking, making quitting easier and relapse less likely.  

The treatment course is 12 weeks:  

Day 1‒3: 0.5 mg tablet, swallowed whole once daily after food  

Day 4‒7: 0.5mg tablet swallowed whole, twice daily after food  

Day 8 onwards: 1mg tablet swallowed whole, twice daily after food  

Patients who cannot tolerate the adverse effects of varenicline can have the dose lowered temporarily or permanently to 0.5mg twice daily.  

The quit date is usually between Day 8 and Day 14.  

While side effects from varenicline are common, most appear to be mild and resolve within the first few weeks of treatment. Common side effects include: 

  • Sore or swollen (inflamed) nose or throat. 
  • Headaches 
  • Diarrhoea 
  • Heartburn  
  • Difficulty sleeping 
  • Feeling dizzy  
  • A bad taste in  mouth.